Publications

Bifurcation in cellular evolution Permalink

Published in , 2022

Modifications to the graph topology of an intracellular catalytic reaction network model lead to a percolation-like phase transition, which is mapped into a bifurcation in the intracellular dynamics, so that the most probable state is suddenly switched from cellular stagnation to exponential growth.

Evolutionary timeline of a modeled cell Permalink

Published in Journal of Theoretical Biology, 2022

A theoretical study of cell evolution is presented here. By using a toolbox containing an intracellular catalytic reaction network model and a mutation–selection process, four distinct phases of self-organization were unveiled.

Preprint version available here